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Frontiers | Dominant Role of CD80–CD86 Over CD40 and ICOSL in the Massive Polyclonal B Cell Activation Mediated by LATY136F CD4+ T Cells
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Expression of the CTLA-4 ligand CD86 on plasmacytoid dendritic cells (pDC) predicts risk of disease recurrence after treatment discontinuation in CML | Leukemia
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Frontiers | CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4
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Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | Genome Medicine | Full Text
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Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4 | Science
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Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis | bioRxiv
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This study identified key differences in transendocytosis by CTLA-4 when activated by CD80 and CD86 ligands; whereby CD80 binding led to targeted ubiquitination and lysosomal degradation while CD86 binding led to enhanced
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3 CD80 and CD86 deliver bidirectional signaling for the activation of T... | Download Scientific Diagram
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